Leibniz Research Alliance

Copper nano structures


Special edition “Nanosafety 2017” in Nanomaterials

The journal Nanomaterials has published an open access special edition, including papers from the Nanosafety conference 2017. The following papers are available on the MDPI website:

  • “Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles”
    by Daniel Stöckmann, Tim Spannbrucker, Niloofar Ale-Agha, Philipp Jakobs, Christine Goy, Nadine Dyballa-Rukes, Tamara Hornstein, Alexander Kümper, Annette Kraegeloh, Judith Haendeler and Klaus Unfried
    PDF Full-text
  • “Low Dose Carbon Black Nanoparticle Exposure Does Not Aggravate Allergic Airway Inflammation in Mice Irrespective of the Presence of Surface Polycyclic Aromatic Hydrocarbons”
    by Karina Lindner, Sina Webering, Michael Stroebele, Henning Bockhorn, Tanja Hansen, Peter König and Heinz Fehrenbach
    PDF Full-text
  • “The DaNa2.0 Knowledge Base Nanomaterials—An Important Measure Accompanying Nanomaterials Development”
    by Harald F. Krug, Nils Bohmer, Dana Kühnel, Clarissa Marquardt, Katja Nau and Christoph Steinbach
    PDF Full-text
  • “Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization”
    by Felipe Vidal, Pilar Vásquez, Francisca R. Cayumán, Carola Díaz, Jorge Fuentealba, Luis G. Aguayo, Gonzalo E. Yévenes, Joel Alderete and Leonardo Guzmán
    PDF Full-text
  • “Implementation of Safe-by-Design for Nanomaterial Development and Safe Innovation: Why We Need a Comprehensive Approach”
    by Annette Kraegeloh, Blanca Suarez-Merino, Teun Sluijters und Christian Micheletti
    PDF Full-text


Saarland University: Lectures about the potential and risks of nanotechnology

On 14 September 2017, scientists from Saarland University and adjacent institutes, including Dr. Annette Krageloh, coordinator of the research alliance Nanosafety, will inform the public in easily understandable terms about nanotechnology. For details, please see the official press release (in German).

New head of priority research area Asthma & Allergy at FZ Borstel

Since 11 April 2017, Prof. Susanne Krauss-Etschmann has been the new director of the priority research area Asthma & Allergy. Her predecessor Prof. Heinz Fehrenbach now focuses entirely on leading his group Experimental Pneumology.

Morpheus – A test platform for the safety of nanomaterials

Sphere of liver cells

3D sphere of liver cells. Cell nuclei are shown in yellow, the actin cytoskeleton in cyan.

The ZIM project MORPHEUS (Morphologic Phenotyping for Establishment of Unique Safety Profiles) aims to develop a multiparametric test platform that can perform an early hazard assessment of nanoparticles. This test platform based on 3D liver microtissue combines the testing of well-established toxicity markers with functional ones (e.g. cytochrome P450 and bile acid profile) after exposure to particles carrying morphological markers. These can be tracked with superresolution STED microscopy. The project also focuses on examining the influence of nanoparticles on the pharmacology of medical drugs. It is run within the ZIM cooperation network Nanopharm and is carried out by Pharmacelsus GmbH and Leibniz Institute for New Materials in Saarbrücken for 3 years.


Environmental particles and allergies

The natural substance ectoin reduces the impact of environmental particles on allergic sensitisation

Airborne toxicants can contribute to triggering allergic diseases in humans. In a current work, researchers of IUF – Leibniz Research Institute for Environmental Medicine show that carbon-particle-induced inflammatory reactions in the lung favour the allergic sensitisation to foreign protein. The natural substance ectoin, which is contained in various medical products, is able to counteract the harmful effects of those environmental particles.

Link to press release (in German only).